Covid? Again.

[Lookinagain]

Follow up call to Dr again today. My face and cheeks hurt so bad I could almost cry. Not a Covid rebound, but a secondary sinus infection. Antibiotics on the way. She said secondary infections are quite common.

I'm so sorry, but hopefully the antibiotics I assume she prescribed will give you some relief quickly.

 

[empliau]

Sinus infections are terrible. I find some relief with a hot pack or, in a pinch, a hot washcloth pressed against the achy sinus.

Feel better soon, @MMtwo

 

[MMtwo]

I'm so sorry, but hopefully the antibiotics I assume she prescribed will give you some relief quickly.

Thanks, me too, I feel awful and fever is back.

Sinus infections are terrible. I find some relief with a hot pack or, in a pinch, a hot washcloth pressed against the achy sinus.

Feel better soon, @MMtwo

Thank you! That sounds good! I would honestly do anything right now to make it feel better. Neti pot is not helping.

 

[AprilBaby]

after negative day 5...back to coughing and another positive test. Rebound Covid.

That stinks, I never had the fever or rebound

 

[Calliecake]

@MMtwo, Sinus infections are miserable. I’m sorry you are still feeling so sick.

@AprilBaby, Did you still feel exhausted after testing negative with this strain of Covid?

 

[MMtwo]

Sinus infections are terrible. I find some relief with a hot pack or, in a pinch, a hot washcloth pressed against the achy sinus.

Feel better soon, @MMtwo

Your advice was helpful. I fell asleep with a wrapped ice pack on my face last night. It cut through the pain. Still a fever today and sleeping, but the face pain has eased.

 

[AprilBaby]

@MMtwo, Sinus infections are miserable. I’m sorry you are still feeling so sick.

@AprilBaby, Did you still feel exhausted after testing negative with this strain of Covid?

I’m still exhausted and it’s been several weeks.

 

[MMtwo]

Finally a negative test this morning - Day 15. The rebound was annoying, uncomfortable, but I would take Paxlovid again in an instant to stay out of the hospital. In recap (for anyone else with rebound):
Test day 1 positive started Paxlovid.
Day 6 negative
Day 8-14 positive rebound (plus sinus infection) miserable, but not as sick as day 1
Day 15 negative

On a do-over, I would wait until late day 2 to start Paxlovid to reduce the chance of a rebound infection.

 

[Lookinagain]

Finally a negative test this morning - Day 15. The rebound was annoying, uncomfortable, but I would take Paxlovid again in an instant to stay out of the hospital. In recap (for anyone else with rebound):
Test day 1 positive started Paxlovid.
Day 6 negative
Day 8-14 positive rebound (plus sinus infection) miserable, but not as sick as day 1
Day 15 negative

On a do-over, I would wait until late day 2 to start Paxlovid to reduce the chance of a rebound infection.

I'm glad to hear you're feeling better and testing negative. Just curious, does delaying the start of Paxlovid actually reduce the risk of a rebound? That's something I'd never heard, but if that is the case, it is good to know.

 

[MMtwo]

I'm glad to hear you're feeling better and testing negative. Just curious, does delaying the start of Paxlovid actually reduce the risk of a rebound? That's something I'd never heard, but if that is the case, it is good to know.

From what Google info I have found. It appears that some people who start very quickly may have more rebound than those that wait until the 2nd day.

I would really prefer to do it only once, next time .

See below at minute 4

 

[LightBright]

I'm glad to hear you're feeling better and testing negative. Just curious, does delaying the start of Paxlovid actually reduce the risk of a rebound? That's something I'd never heard, but if that is the case, it is good to know.

Yes, there’s data suggesting starting later reduces rebound.

Here’s a link to a paper explaining what rebound is and showing that time the medication was started is a factor in rebound.

An explanation for SARS-CoV-2 rebound after Paxlovid treatment - PMC

In a fraction of SARS-CoV-2 infected individuals treated with the oral antiviral Paxlovid, the virus rebounds following treatment. The mechanism driving rebound is not understood. Here, we show that viral dynamic models based on the hypothesis that ...

www.ncbi.nlm.nih.gov

 

[MMtwo]

Yes, there’s data suggesting starting later reduces rebound.

Here’s a link to a paper explaining what rebound is and showing that time the medication was started is a factor in rebound.

An explanation for SARS-CoV-2 rebound after Paxlovid treatment - PMC

In a fraction of SARS-CoV-2 infected individuals treated with the oral antiviral Paxlovid, the virus rebounds following treatment. The mechanism driving rebound is not understood. Here, we show that viral dynamic models based on the hypothesis that ...

www.ncbi.nlm.nih.gov

Thanks for this! Also, I can confirm, I started the first day of symptoms. D'oh!

 

[Austina]

I hope you feel better soon

 

[MMtwo]

I tested negative this morning and feeling mostly back to normal, same a small cough and congestion.

 

[MMtwo]

I hope you feel better soon

Thank you on the mend now.