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HRT - Care To Share Your Experiences?

Oh, Ally, that sounds awful, and with the stress (and excitement) of your massive renovation, it must be pretty miserable. I agree with the others that it sounds like the GP has given you poor and outdated advice. I'm another very firm advocate of bioidenticals for anyone who's suffering. At my annual appointment last week, my gynae mentioned that she has some patients who have had breast cancer who are okayed by their oncologists to go on bhrt as the quality of life issues outweigh the risks. I never got on with hormonal birth control at all (and had terrible hyperemesis gravidarum all three pregnancies) and have been absolutely fine and, in fact, someone would have a very difficult time persuading me to give it up, both for all the protections mentioned, but also because it makes life so, so much nicer.

I hope the other GP is more sympathetic and more clued up. In case you're not happy with their response, the Marion Gluck Clinic in London does remote appointments. I used to go there but now use this clinic https://londonbioidenticalhormones.com
However, I'm not sure if they're taking new patients. The Marion Gluck Clinic isn't the most intensely personal experience in the world, but I found them fine and pretty good at tailoring the regimen - I believe (although could be wrong about this) that oral hrt carries more risk than transdermal. I'm also very sensitive to both progesterone and testosterone, so mine requires fairly careful balancing and took some tweaking, which they were very good at. I get reviewed every six months (more if needed) and the prescriptions are made up by this place and sent to me

With your symptoms I'd also suggest asking for a full autoimmune/thyroid panel, and do specify full as they are likely to only run the TSH test unless pushed. Any time of hormonal change can be a trigger point for thyroid issues, etc. to crop up, so it's worth making sure nothing else is going on.

I hope you feel better soon!

Thanks so much for all of this information! I am glad you have found someone to listen to you & a balance that works. It’s definitely a tricky time & I’m keeping my fingers crossed that my chat with the GP is informative & positive. Will keep you posted.
 
It would be interesting to see whether I could get on this since I had hormone receiptor positive breast cancer in 2019 after which the chemo abrubtly thrust me into menopause. After chemo, I had the “implant” (zolodex) quarterly for two years to get to the approximate date I might have become naturally menopausal. I also take (and will continue for like 10 years) what I call ”man pills” (estrogen suppressors/aromatase inhibitors) to keep the E&P+ cancer from growing and also a baby dose of venlafaxine to supposedly help with night sweats. Which I don’t really get. It also helps with anxiety though, which I do feel that I have.

I don’t really want to continue on venlafaxine forever, and I would love to see if maybe testosterone could help me get back some libido which has been majorly affected by the zolodex, venlafaxine and/or man pills.

In a case like mine, a bio identical hormone is still a hormone, right? So wouldn’t taking E or P (even from my own biological source) still cause hormone receptor positive cells to recept… i.e, grow? We wouldn’t really want that to happen, but staying on the aromatase inhibitor makes my husband joke that he and I will soon be having a beard growing contest (kidding) (sort of).
 
It would be interesting to see whether I could get on this since I had hormone receiptor positive breast cancer in 2019 after which the chemo abrubtly thrust me into menopause. After chemo, I had the “implant” (zolodex) quarterly for two years to get to the approximate date I might have become naturally menopausal. I also take (and will continue for like 10 years) what I call ”man pills” (estrogen suppressors/aromatase inhibitors) to keep the E&P+ cancer from growing and also a baby dose of venlafaxine to supposedly help with night sweats. Which I don’t really get. It also helps with anxiety though, which I do feel that I have.

I don’t really want to continue on venlafaxine forever, and I would love to see if maybe testosterone could help me get back some libido which has been majorly affected by the zolodex, venlafaxine and/or man pills.

In a case like mine, a bio identical hormone is still a hormone, right? So wouldn’t taking E or P (even from my own biological source) still cause hormone receptor positive cells to recept… i.e, grow? We wouldn’t really want that to happen, but staying on the aromatase inhibitor makes my husband joke that he and I will soon be having a beard growing contest (kidding) (sort of).

Obviously I cannot offer any advice as I am completely in the dark on all of this, but i am sorry to hear about your breast cancer & I am glad you are healthy & doing ok. Hugs to you.
 
My menopause symptoms started about 6 months after my hysterectomy in 2015. I used the Climara patch for about 6-1/2 years then it stopped working. Hot flashes and other symptoms returned.

I looked into bioidentical hormone replacement therapy (BHRT) after a friend told me of her experience using them. I started in September and just had my third dose this week. I get estrogen and testosterone pellets inserted in my upper buttocks area. So far, I am super pleased with the results. No more hot flashes, have more patience, more energetic and increased sex drive.

Hope you find a solution for your symptoms.
 
Thank you all for telling me your experiences :kiss2:

I had a great appoint with my GP on Wed. We had a long chat about HRT, about my concerns, about how I have been managing so far etc & mostly about what I am struggling with & need some help.

She didn’t lecture of dismiss. She actually said “what can I do for you to help this be easier?”

She arranged bloods to rule out any arthritis or bone issues, which I had early the next morning, plus to measure my current hormone levels. She prescribed a 3 month trial of the patches, which I can slap on my arse when my period starts next week, with a view to seeing if it makes any difference or not. At that stage we will discuss whether to continue, whether to add any creams or gels, or whether to knock it on the head & stop. I am reluctant but also excited to get going. As a life long natural girl who is generally holistic, I will hold up my hands & agree to see how this goes.
 
@Ally T I am going to message you on FB with the group I highly recommend (I am biased because I mod that group but it is an excellent group despite that haha). Everything you ever wanted to know about BHRT and more. It's a great group.

I would love the info to this group as I am dealing with the same issues.
 
Question for all of you who have been there: how did you know you were in perimenopause and needed HRT? Asking because some of the peri symptoms overlap with some autoimmune symptoms. I was curious about what was going on with me last year—regular periods but some other symptoms that could either be autoimmune or perimenopause. My endocrinologist ran tests for ovarian reserve and told me I’m nowhere near menopause. Wondering how reliable that is. No maternal pattern to go of of because my mother had a hysterectomy in her 30s.
 
Question for all of you who have been there: how did you know you were in perimenopause and needed HRT? Asking because some of the peri symptoms overlap with some autoimmune symptoms. I was curious about what was going on with me last year—regular periods but some other symptoms that could either be autoimmune or perimenopause. My endocrinologist ran tests for ovarian reserve and told me I’m nowhere near menopause. Wondering how reliable that is. No maternal pattern to go of of because my mother had a hysterectomy in her 30s.

According to UK health information, perimenopause can last for as long as 10 years before the menopause actually happens. So these changes can creep slowly in hardly noticed, becoming more severe, before you periods even think about becoming erratic etc. It’s a much bigger picture than periods alone & I am thankful that this is acknowledged & recognised now, as so many women suffer in silence because they are still getting monthlies.

I have had peri symptoms for years & as I have a bleeding disorder that requires yearly blood work, they have been throwing other tests in at the same time. These have included thyroid function, auto immune conditions & rheumatoid arthritis. These tests are always negative & despite regular periods, we have known for at least 3-4 years that I am well into peri with very low oestrogen, progesterone & testosterone.

I have always coped very well with exercise & supplements up until more recently, so I thought I was sailing through quite well. But my body has upped it’s anti & supplements are no longer cutting it. My feet & hips are too painful to run on & i am having to change the bed more frequently due to being soaked with sweat. Yummy! My periods are still monthly, but getting slightly further apart. I used to be 28 days on the clock, but now can range from 27 to 34 days. However this is a new thing for me & only a small part of the puzzle.

I hope you are able to find someone to have a conversation with who will listen to you. Here in the UK they don’t routinely do hormone level checks anymore, but will prescribe HRT on symptoms alone if you are over 45.
 
I’m 54 and have a Mirena which my GP and Gynaecologist support but my recent hormone blood tests have showed as post menopause which both professionals view as inconclusive results.

My GP has a side profession of skin treatment and advancement, her view is that I continue with a Mirena as she believes it provides strong anti ageing when it comes to skin health and general health at my age.

My Gynaecologist would like it removed and see what my actual hormone levels are and then look at what is the best cause of action once the true results are discovered.
He is also concerned that there are issues that need to be looked after health wise if I’m post menopausal eg; heart and bone mass loss.

Whose advise do I concentrate on? Naturally the Gynaecologist is the expert in this area but my GP has a strong community of female patients my age and beyond who have always had good outcomes (not necessarily skin) in female health, menopause & general.

I would appreciate your thoughts!
 
I’m 54 and have a Mirena which my GP and Gynaecologist support but my recent hormone blood tests have showed as post menopause which both professionals view as inconclusive results.

My GP has a side profession of skin treatment and advancement, her view is that I continue with a Mirena as she believes it provides strong anti ageing when it comes to skin health and general health at my age.

My Gynaecologist would like it removed and see what my actual hormone levels are and then look at what is the best cause of action once the true results are discovered.
He is also concerned that there are issues that need to be looked after health wise if I’m post menopausal eg; heart and bone mass loss.

Whose advise do I concentrate on? Naturally the Gynaecologist is the expert in this area but my GP has a strong community of female patients my age and beyond who have always had good outcomes (not necessarily skin) in female health, menopause & general.

I would appreciate your thoughts!

Gosh, this is a really tricky one & I am no help at all, because I am only just starting my HRT journey.

I am sure others will chime in & offer advice, though.

Calling @missy She has a wealth of knowledge about this sort of thing.
 
Gosh, this is a really tricky one & I am no help at all, because I am only just starting my HRT journey.

I am sure others will chime in & offer advice, though.

Calling @missy She has a wealth of knowledge about this sort of thing.




I’m 54 and have a Mirena which my GP and Gynaecologist support but my recent hormone blood tests have showed as post menopause which both professionals view as inconclusive results.
My GP has a side profession of skin treatment and advancement, her view is that I continue with a Mirena as she believes it provides strong anti ageing when it comes to skin health and general health at my age.


My Gynaecologist would like it removed and see what my actual hormone levels are and then look at what is the best cause of action once the true results are discovered.
He is also concerned that there are issues that need to be looked after health wise if I’m post menopausal eg; heart and bone mass loss.

Whose advise do I concentrate on? Naturally the Gynaecologist is the expert in this area but my GP has a strong community of female patients my age and beyond who have always had good outcomes (not necessarily skin) in female health, menopause & general.

I would appreciate your thoughts!

I don't love the Mirena as it is synthetic and not bio identical. I agree with your gynecologist and would remove it and see what happens to your hormone levels. Then I would start bio identical HRT as needed depending on your symptoms, signs and blood work.
 
@missy thank you for your response, I agree with my gynaecologist’s view too and will go ahead with his proposal. I will discuss a bio identical HRT routine and hopefully this will be a successful course of action.

Thanks @Ally T for your support and good luck with your Menopause journey. It’s certainly a complex issue for most of us.
 
Bumping this thread to ask you ladies if you found the secret to losing weight during peri & meno?

I have gained 18 lbs over the last 4 years. I was quite slim to start with, but now I am a solid UK size 14 (a US 10) & I hate to say it & I know I should be kinder to myself with all that is going on, but I am repulsed by how I look & how my clothes fit.

I eat healthily 90% of the time, treats & alcohol at weekends only. I have stopped running due to painful joints, but hoping the HRT will deal with that & I can start again. But I am still active & replaced my 30k a week with a 6k power walk every week day. However, my thighs, waist & upper arms are betraying me terribly!

There has been a gym built at the Vicarage behind the new garage block & we are waiting delivery of the most spring loaded running machine I could find, plus weights benches, a rower & a static bike. I am hoping I can get back into shape, as I really can’t be anymore active in my day to day life, or eat any more healthily.

Urgh!

Care to share how you managed to get hormonal weight off? Did the HRT boost your metabolism back to where it used to be? Were you able to get more active?
 
Bumping this thread to ask you ladies if you found the secret to losing weight during peri & meno?

I have gained 18 lbs over the last 4 years. I was quite slim to start with, but now I am a solid UK size 14 (a US 10) & I hate to say it & I know I should be kinder to myself with all that is going on, but I am repulsed by how I look & how my clothes fit.

I eat healthily 90% of the time, treats & alcohol at weekends only. I have stopped running due to painful joints, but hoping the HRT will deal with that & I can start again. But I am still active & replaced my 30k a week with a 6k power walk every week day. However, my thighs, waist & upper arms are betraying me terribly!

There has been a gym built at the Vicarage behind the new garage block & we are waiting delivery of the most spring loaded running machine I could find, plus weights benches, a rower & a static bike. I am hoping I can get back into shape, as I really can’t be anymore active in my day to day life, or eat any more healthily.

Urgh!

Care to share how you managed to get hormonal weight off? Did the HRT boost your metabolism back to where it used to be? Were you able to get more active?

Ally, first of all happy Mother's Day. Wishing you and your family a very happy Mother's day and all the best wishes for you in your gorgeous new home.

Second of all yes. once your hormones are optimized *and* balanced the weight should come off and stabilize. Any BHRT protocol ideally needs to ensure adequate and balanced blood levels of all three sex hormones to help address weight and metabolism. Low Estrogen can cause increasing insulin resistance, which in turn can contribute to weight gain. Progesterone is a natural diuretic. And Testosterone helps maintain muscle mass. Plus make sure your thyroid is optimized as well as a sluggish one will lead to weight gain. Once all your hormones are both balanced and optimized you will see results and likely feel much better too
 
Ally, first of all happy Mother's Day. Wishing you and your family a very happy Mother's day and all the best wishes for you in your gorgeous new home.

Second of all yes. once your hormones are optimized *and* balanced the weight should come off and stabilize. Any BHRT protocol ideally needs to ensure adequate and balanced blood levels of all three sex hormones to help address weight and metabolism. Low Estrogen can cause increasing insulin resistance, which in turn can contribute to weight gain. Progesterone is a natural diuretic. And Testosterone helps maintain muscle mass. Plus make sure your thyroid is optimized as well as a sluggish one will lead to weight gain. Once all your hormones are both balanced and optimized you will see results and likely feel much better too

Funny you should say that, but when my blood results came back my GP said “your oestrogen is far lower than it should be for your age.” I have been having symptoms for years & years, though still have regular periods. It’s not all about periods though, is it?

My GP has been fabulous & I know when I got back in 2 months she will have a clearer picture of what’s going on.
 
Bumping this thread to ask you ladies if you found the secret to losing weight during peri & meno?

At my last physical, my GP and I discussed my weight gain and struggle to lose. I have always been US size 14/16 and recently jumped 15lbs and two sizes. she recommended I add more protein and fiber as well as some intermittent fasting. I already do the fasting bit, 16-20hr most days.

The past 3 weeks I have focused on protein and fiber and have lost 6lbs without any other adjustments. I added more beans, lean meats grilled chicken/turkey, fish nuts, seeds and half an avocado.

I track how many grams of each I am getting on a food app and try to get 20+grams of fiber and 150-175 grams of protein each day.

Small shifts in diet seem to have helped, but I don’t know how long it will continue to help me lose weight.
 
Reading this thread with interest.

I am 46 next birthday and am definitely starting to feel the twinges of age. I’ve gained 25 pounds over the last three years having been slim UK 10 for years since I lost the baby weight. I also find myself being very irritable and grumpy, and very little sex drive, which isn’t usually like me. But maybe that’s partly the weight gain?

I have always had irregular periods and a long cycle as I have PCOS so hard to tell if that’s really impacted. I’ve got an appointment with the GP next week to get my hormone levels checked.

Like another poster on here I have never got along well with hormonal contraceptives and always had an IUD due to that. The combined pill gave me headaches and made me gain weight. The progesterone only pill made me severely depressed. So I’m kind of worried about messing with my hormone levels at all.
 
Reading this thread with interest.

I am 46 next birthday and am definitely starting to feel the twinges of age. I’ve gained 25 pounds over the last three years having been slim UK 10 for years since I lost the baby weight. I also find myself being very irritable and grumpy, and very little sex drive, which isn’t usually like me. But maybe that’s partly the weight gain?

I have always had irregular periods and a long cycle as I have PCOS so hard to tell if that’s really impacted. I’ve got an appointment with the GP next week to get my hormone levels checked.

Like another poster on here I have never got along well with hormonal contraceptives and always had an IUD due to that. The combined pill gave me headaches and made me gain weight. The progesterone only pill made me severely depressed. So I’m kind of worried about messing with my hormone levels at all.

Non bio identical is a completely different animal to bio identical. I too was never able to tolerate synthetic non bioidentical bc pills. However bio identical is absolutely different. A complete 180 and I had no issues not only tolerating it but thriving and let me tell you no one is more sensitive than I am to medication. However bio identical is the exact same molecular structure as what our bodies used to produce in sufficient quantity.

Non bio identical HRT are synthetics that are produced by big pharma and are FDA approved. These are the most risky types of hormone replacement according to the research (especially in oral form). These synthetic options do not fully match (at a molecular level) the hormones that our body naturally produces. Women should avoid this category and consider these options a last resort.

Examples of oral synthetic HRT include: Premarin, Prempro, Duavee, Kilofem, Elleste Duet, Femoston, Tibolone, hormonal birth control pills, etc. Non-oral options would include things like the combi-patch (bio/body-identical estrogen but synthetic progestin). And then any form of synthetic progestin like the Mirena IUD, Norethisderone, etc. Premarin vaginal cream also falls into this category.

Bio identical examples that are FDA approved include Estradiol patches, gels, injections, and oral pills. Anything that is just plain “Estradiol” is bioidentical. For progesterone, you have bioidentical micronized progesterone pills (Prometrium), which can also be used as suppositories. And all forms of mainstream vaginal hormonal products also fall into this category except Premarin cream. The combined pill "Bijuva" falls into this category but note that it is the ONLY bioidentical combined pill. Any other mainstream combined E/P pills are synthetic.

Then there is compounded bio identical and that includes custom compounded creams, compounded pills, compounded troches, etc. At a molecular level, the hormones in this category are no different than those in the above category. What differs are the inactive ingredients, sometimes dosing, sometimes delivery method, and different (less) oversight or regulation by government agencies. Most women use testosterone from this category (not all, but most). Outside of the U.S. (and Canada to a certain extent) compounded hormones are less common.


Just an FYI. I ask everyone to do their due diligence and do NOT let the medical community guide you here because, for the most part, they are woefully behind the times and are not taught these facts in medical school. It is only the healthcare professional who wants to learn who will be able to work with you and get your hormones optimized and balanced for relief of symptoms and for maximum health benefits
 
Funny you should say that, but when my blood results came back my GP said “your oestrogen is far lower than it should be for your age.” I have been having symptoms for years & years, though still have regular periods. It’s not all about periods though, is it?

My GP has been fabulous & I know when I got back in 2 months she will have a clearer picture of what’s going on.

You can be having regular periods but not ovulating ... why don't you get an ovulation test kit and see if you are indeed no longer ovulating.
 
You can be having regular periods but not ovulating ... why don't you get an ovulation test kit and see if you are indeed no longer ovulating.

This is actually a really good idea! Are they accurate?
 
@missy Are you available on IG(or other location of choice) to ask some questions on BHRT?
 
Hello Meno Warriors!

I though I would re-activate this thread with an update & a couple of questions.

I started on a combined patch 15 months ago, which whilst it dealt with many of my symptoms, it caused me to start to lose a lot of hair. The GP was amazing & worked out that the synthetic progesterone in this patch was the same as the one in the Mirena IUD, which I had removed after 8 weeks for the same reason in 2016.

I moved onto Oestrogen Gel & a Bio Identical progesterone tablet. The hair loss ceased immediately but after 3 months, my symptoms were fully returning. At that point the GP put me onto a larger dose of Oestrogen via a patch, but the patch was huge & kept peeling off in the shower. In February this year I moved onto Estradiol, a Bio Identical patch, which is tiny & has been amazing! The combo of these 2 have been brilliant, despite still having some symptoms & zero libido.

My breakthrough bleeds with the Prog have been regular & normal, until 6 weeks ago. I’d had a teeny bit of spotting & then when my breakthrough started, it was literally 2 sanitary pads worth & stopped within a few hours. My next scheduled breakthrough made up for it & was heavy & 7 days long. I finished that bleed 10 days ago & on Wednesday this week, started to bleed heavily again, so only about 16 days after the previous bleed started. I called my GP yesterday & she referred me for a pelvic ultrasound. This is arranged for next Thursday.

I am sh!tting my pants. I don’t get any abdominal pains (apart from at the start of a breakthrough as I would a period, but none with this new bleed) & don’t suffer with bloating - this bleed is just out of the blue & I panicked that I’d wet myself when it first started. It’s now been 2 full days or what can only be described as a full on period, only lighter than my usual bleeds & a pad is lasting a few hours instead of my usually hourly change (I bleed excessively).

The GP seems to think it’s an imbalance of my HRT, probably caused due to a fluctuation of my natural, waining hormones (I recently turned 50) that has trigged the bleed. Her words were “It’s standard to refer for an urgent pelvic exam, but I am pretty certain it’s due to the HRT. Once the scan is done & clear, I will send you to a private HRT clinic for tweaking that I am not able to do here within the NHS.”

So. That leaves me with a week of panic & terror. One of my friends had something similar earlier this year (she takes the same Bio HRT as I do) with a heavy bleed every 14 days for 3 months. Her scan was clear & they never found the cause. It settled again & hasn’t happened to her since.

@missy Is this a common thing to happen? I am pretty stressed & debated pulling off my magic patch yesterday & doing away with it all, even though I know it’s hopefully nothing sinister. And if I do need some treatment of any sort, I am glad I was paranoid enough to call the GP after such a short time of ‘not normal for me’ activity.

Anybody care to share / offer reassurance?
 
Have you considered going off of replacement hormones - at least internal or transdermal ones - entirely? I think that traditionally, HRT was offered for women going through menopause or adjusting to being post-menopausal. It wasn’t intended to be taken for the rest of one’s life. You are at an age where most women would be post-menopausal, as opposed to going through menopause. I went through a very early menopause and then took HRT for 15-20 years until I just got tired of it. Yes, there are some downsides to quitting but - some of them can be dealt with, and others I just accept as part of the privilege of getting older.
 
Have you considered going off of replacement hormones - at least internal or transdermal ones - entirely? I think that traditionally, HRT was offered for women going through menopause or adjusting to being post-menopausal. It wasn’t intended to be taken for the rest of one’s life. You are at an age where most women would be post-menopausal, as opposed to going through menopause. I went through a very early menopause and then took HRT for 15-20 years until I just got tired of it. Yes, there are some downsides to quitting but - some of them can be dealt with, and others I just accept as part of the privilege of getting older.

Well I wanted to rip that little patch off yesterday, I can tell you! But also as a friend at work pointed out, at having just turned 50 years old, my body is in hormonal chaos. I was still regularly bleeding every month before the HRT, which I only started 15 months ago, so unlikely I will be post-meno just yet. If I wasn’t on HRT, I suspect my periods would be naturally haywire by now. And I had tried every supplement out there to try & navigate this journey naturally, but I was at the end of my tether. HRT really was a considered & prolonged decision, which has worked out brilliantly so far. Just wondering what maybe causing this sudden ‘extra’ bleed?
 
HRT saved my sanity, don't give up on finding the right combination. The breakthrough bleeding is super common. As long you get your surveillance ultrasound to make sure your endometrium is behaving there is no reason to freak out. I had a lot of bleeding on the oral progesterone. Many times I wished I didn't have a uterus but it seems extreme to get it yanked out at this point. Kidding, not kidding.
 
HRT has so many benefits. I do hope you can stay on it. Breakthrough bleeding can be normal and it sounds like you have a fantastic doc who is doing their due diligence. I can sense how frustrated you are. It is a very nuanced thing, as each of us are so different when it comes to dosing! I am so glad I’m on it and while it does take some patience to dose correctly, I’ve found it to be a game changer for me. I hope you can get this figured out and quickly! As far as your libido, sounds like testosterone would be helpful. I am also on that and wow big difference. My libido was basically non existent but within a couple weeks I noticed that improving, as well as my energy and recovery from my workouts is faster and I’m starting to build more muscle. Best of luck, @Ally T !
 
@Ally T do not go off BHRT. It is very common to experience this and it is most likely due to an imbalance of e to p. Did you join the BHRT group I recommended? I wrote a featured thread on spotting and I think you would find it helpful. Do you know your labs? That will show the issue. You need the LC MS P blood test (since you are taking p orally) and the estradiol blood test and I bet that will solve this mystery. Please do not worry and please do not give up. It is all about optimizing and balancing these hormones and you can do it!!! Let me know if you need my help off PS

ETA and stay away from NON bio identical. Progestin is a NO. You always want bio identical. Prometrium. Estradiol. Testosterone
 
I would love to join the fb group. Currently on combipatch. I seem to be tolerating it OK. No bleeding.
 
I would love to join the fb group. Currently on combipatch. I seem to be tolerating it OK. No bleeding.

Do you have my ig handle? If you message me I’m happy to link you to the group
 
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